Japan at the Yoshida clan compound, Logan kneels at Mariko Yoshida’s grave and apologizes because he can not spend time with her, he must go protect his family and friends. Logan stops at the hospital and visits Yukio. Yukio tells Logan that she doesn’t want him to see her, because she is paralyzed. Yukio tells Logan that it is Omega Red and Lady Deathstrike that attack her and kidnapped Amiko. Logan tells Yukio that he will get them. Yukio tells him that they left him a message, carved into her back. Logan looks at her back and it says if he wants Amiko alive, go to the Hotel Bellagio in Las Vegas. Yukio tells Logan that if she isn’t able to walk again she wants him to kill her. Logan tells her that he can’t, Yukio tells him that if he doesn’t there are plenty of others that will. Logan tells him that he understands and to let him think about it.

Weapon X facility, Agent Kane searches the computers and finds that it was Sabretooth that used the MCP gun and tells the Director that Sabretooth has stolen funds from the project and copied the Logan Files. Agent Jackson starts yelling at the Director that he told him not to trust Sabretooth, but the Director wouldn’t listen. The Director slaps agent Jackson.

Hotel Bellagio in Las Vegas, Logan walks through the front door, but doesn’t see anybody, suddenly Omega Red uses his tentacles to throw Logan through a window, so Logan gets up and grabs Omega Reds tentacle and pulls him to the floor. Lady Deathstrike slashes Logan over and over again. Logan rips his jacket off, revealing that he is wearing a guardian suit. Omega Red releases his death spores, which make Logan weak, so he kicks Lady Deathstrike into Omega Red and runs off.

Weapon X facility, Agent Jackson gets up and runs at the director, Agent Kane stops Jackson from hitting the Director, but the Director demands that Kane let Jackson go. Jackson goes to hit the Director, but he can’t. The Director picks up a chair and hits Jackson with it and explains that he had agent Jackson implanted with a chip that will prohibit him from inflicting aggression on a superior. The Director has his men carry Jackson away and tells Agent Kane to prepare the teleporters. Agent Kane tells him that Sabretooth has blocked their access to the machine, but he has found that Sabretooth has been teleporting Lady Deathstrike and Omega Red around. Agent Kane tells the Director that he has reprogrammed the computer so when Sabretooth uses the telepoter he will be sent to them.

Hotel Bellagio in Las Vegas, Lady Deathstrike and Omega Red chase Logan into another room, but they loose Logan in the crowd. Logan jumps out and kicks Omega Red and steals Deathstrike’s mask, which protects her from Omega Red’s death spore. Logan sprays Omega red with smoke and climbs up a rope, but Deathstrike stabs Logan in the leg. Logan cuts the rope, which cause Deathstrike to fall to the floor. Logan escapes through the ceiling, which is the floor above it and lays there for a second weak from his loss of blood. Omega Red grabs Logan and throws him out the window. Logan splashes into a fountain below. Lady Deathstrike and Omega Red beat and claws Logan and then drag him up to Sabretooth’s room. Logan opens his eyes to see Sabretooth siting on the couch with Amiko, who is tied up.